We have assembled a new team of health care professionals with intersecting expertise in clinical HIV and neuroscience medicine, fundamental science, health outcomes and applied statistics to understand and improve brain health in HIV.
The objectives are to contribute evidence for the validity of a brief brain health assessment approach, to estimate the extent to which HIV-related cognition-relevant clinical factors and patient-centered outcomes inter-relate and evolve over time, allowing identification of the mechanisms underpinning longitudinal changes in brain heath.
A total of 900 participants from across Canada will be recruited and characterized prospectively over a 27-month period to answer questions about evolution of outcome interests. All participants will be offered basic brain health information. Participants are not required to take any special medications they are asked to complete a questionnaire every 9 months detailing demographic information, vitality, stress, social support, sleep, cognition, quality of life, HIV and psychological symptoms. Participants will also have their cognition assessed at each visit and provide blood and saliva samples for future immunological, virological or genetic studies.